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Cardiovascular Disease, Cardiovascular Health
Cardiovascular Support, Vitalzym Seb

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Vitalzym SEB 

Also Below Read "The Real Causes of Heart Attacks".

"We set out to formulate the most effective systemic enzyme blend specifically for cardiovascular health, and our formulation, which contains Sebkinase, has met that challenge."
Specialty Enzymes, 2005

Vitalzym SEB is formulated with your cardiovascular well-being in mind. The SEBkinase blend contains "heart healthy" enzymes that may cleanse the blood of excess fibrin and reduce vascular inflammation. It also contains powerful antioxidants, such as CoQ10 that has been shown to have significant impact on heart function. Introduced in 2002, the original Vitalzym has become the leading systemic enzyme formulation recommended for pain, inflammation, and scar tissue. Countless sufferers of chronic conditions, such as arthritis, fibromyalgia, systemic inflammation, fibroids, and many more have found relief with the regular use of Vitalzym. A common benefit of Vitalzym has been its ability to cleanse the blood and reduce vascular inflammation. World Nutrition and Specialty Enzymes have taken the cardiovascular benefits of Vitalzym and harnessed them with nattokinase and other "heart healthy" nutrients to create an enzyme formulation specifically for cardiovascular wellness.

Reduce Fibrin in the Blood
The fibrinolytic enzymes in VitalzymSEB have been shown to have the ability to digest excess fibrin (protein buildup) in the blood, allowing for improved blood viscosity. Stacked red blood cells (or Rouleau effect) often reflect poor protein digestion. Symptoms can include fatigue, stress on the heart, and poor circulation. The ingredients in VitalzymSEB have been shown, using darkfield microscopy, to significantly reduce stacked red blood cells. Below, you can see the effect of proteolytic enzymes reducing stacked red blood cells.
Reduce Vascular Inflammation
Recent studies have shown the correlation between elevated vascular inflammation and heart disease. The enzymes in VitalzymSEB have been shown to reduce the levels of C-Reactive Proteins (inflammation marker).
Frequently Asked Questions

Ingredients for Vitalzym SEB:
Proprietary Blend contains SEBkinase (blend of Nattokinase and Serratiopeptidase), Bromelain, Papain, Lipase, Protease, Rutin, Amla, CoQ10, and Magnesium

Nattokinase
Nattokinase is a profibrinolytic enzyme extracted and purified from the essence of natto, a fermented soybean food used by the Japanese for thousands of years as a traditional food medicine. Nattokinase was first identified in 1980 by Dr. Hiroyuki Sumi, M.D., Ph.D., who was researching thrombolytic enzymes with the hope of finding a natural agent that could successfully dissolve thrombus associated with cardiac and cerebral infarction (blood clots associated with heart attacks and stroke). After testing more than 200 natural foods as potential thrombolytic agents, Sumi found that natto possessed a substance with "a potency matched by no other enzyme." Dr. Sumi named the newly discovered enzyme nattokinase. By dissolving fibrin more completely than any other substance tested by Dr. Sumi, nattokinase is particularly effective in helping the body fight blood clots. Its thrombolytic activity is enhanced by the enzyme’s ability to boost the body’s production of both plasmin and other clot-dissolving agents, including endogenous urokinase. Many healthcare professionals believe nattokinase to be superior to conventional clot-dissolving drugs. Nattokinase is also characterized by its unmatched length of activity, which ranges from 8- 12 hours after it is orally consumed. This is in stark contrast to the antithrombin drugs that wear off within minutes following IV treatment. This activity is achieved in two ways:
nattokinase prevents coagulation of blood, and it dissolves existing thrombus. Both the efficacy and the prolonged action of nattokinase can be determined by measuring levels of EFA (euglobulin fibrinolytic activity) and FDP (fibrin degradation products), which both become elevated as fibrin is being dissolved. By measuring EFA & FDP levels, activity of nattokinase has been determined to last from 8 to 12 hours. An additional parameter for confirming the action of nattokinase following oral administration is a rise in blood levels of TPA antigen (tissue plasminogen activator), which indicates a release of TPA from the endothelial cells and/or the liver.
Nattokinase has been the subject of 17 studies, including two small human trials.
Dr. Sumi and his colleagues induced blood clots in male dogs, then orally administered either four capsules of nattokinase (250 mg per capsule) or four placebo capsules to each dog. Angiograms (X-rays of blood vessels) revealed that the dogs who received nattokinase regained normal blood circulation (free of the clot) within five hours of treatment. Blood clots in the dogs who received only placebo showed no sign of dissolving in the 18 hours following treatment.

Researchers from Biotechnology Research Laboratories and JCR Pharmaceuticals Co. of Kobe, Japan, tested nattokinase's ability to dissolve a thrombus in the carotid arteries of rats. Animals treated with nattokinase regained 62 percent of blood flow, whereas those treated with plasmin regained just 15.8 percent of blood flow.1 Researchers from JCR Pharmaceuticals, Oklahoma State University, and Miyazaki Medical College tested nattokinase on 12 healthy Japanese volunteers (6 men and 6 women, between the ages of 21 and 55). They gave the volunteers 200 grams of natto (the food) before breakfast, then tracked fibrinolytic activity through a
series of blood plasma tests. The tests indicated that the natto generated a heightened ability to dissolve blood clots: On average, the volunteers' ELT (a measure of how long it takes to dissolve a blood clot) dropped by 48 percent within two hours of treatment, and volunteers retained an enhanced ability to dissolve blood clots for 2 to 8 hours. As a control, researchers later fed the same 30 amount of boiled soybeans to the same volunteers and tracked their fibrinolytic activity. The tests showed no significant change.
The Benefits of Nattokinase on Blood Pressure
Traditionaly in Japan, Natto has been consumed not only for cardiovascular support, but also to lower blood pressure. In recent years, this traditional belief has been confirmed by several clinical trials. In 1995, researchers from Miyazaki Medical College and Kurashiki University of Science and Arts in Japan studied the effects of nattokinase on blood pressure in both animal and human subjects (see below). In addition, the researchers confirmed the presence of inhibitors of angiotensin converting enzyme (ACE), which converts angiotensin I to its active form angiotensin II within the test extract, which consisted of 80% ethanol extract of lyophilized viscous materials of natto. ACE causes blood vessels to narrow and blood pressure to rise - by inhibiting ACE, nattokinase has a lowering effect on blood pressure.

Animal Study
After a single intraperitoneal administration of 400-450 grams of the test extract (equivalent to 25 mg of natto food) into male Wister rats, systolic blood pressure (SBP) significantly decreased from 166 + mmHg to 145 + 24 mmHg in just two hours (p<0.05), and decreased further to 144 + 27 mmHg in 3 hours (p<0.05). On average, this data represents a 12.7 percent drop in SBP within two hours.
Human Study
The same natto extract was then tested on human volunteers with high blood pressure.
Blood pressure levels were measured after 30 grams of lyophilized extract (equivalent to 200 grams of natto food) was administered orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure (SBP) decreased on average from 173.8 + 20.5 mmHg to 154.8 + 12.6 mmHg. Diastolic blood pressure (DBP) decreased on average from 101.0 + 11.4 mmHg to 91.2 + 6.6 mmHg. On average, this data represents a 10.9 percent drop in SBP and a 9.7 percent drop in DBP.
Conclusion
The traditional Japanese food Natto has been used safely for over 1000 years. The potent fibrinolytic enzyme nattokinase appears to be safe based upon the long-term traditional use of this food. Nattokinase has many benefits including convenience of oral administration, confirmed efficacy, prolonged effects, cost effectiveness, and can be used preventatively. It is a naturally occurring, food-based dietary supplement that has demonstrated stability in the gastrointestinal tract, as well as to changes in pH and temperature.


Dosage: The recommended dosage is 1 capsule 3 times daily. Dr. Wong strongly recommends not to exceed this dosage without strict supervision from your medical provider. This product is not for hemophiliacs or those on anticoagulants.

Is there any toxicity?

There have been no reports of toxicity from the ingredients, however nattokinase can significantly cleanse, therefore thin, the blood. We suggest staying within the recommended dosage.

What is the difference between Vitalzym and VitalzymSEB? VitalzymSEB was formulated specifically for cardiovascular health. There is a significant amount of nattokinase in the product that may help cleanse arterial plaque. It may also help to reduce fibrin in the circulatory system and help to reduce vascular inflammation. Vitalzym was formulated specifically for pain, inflammation, and systemic fibrosis. Vitalzym's chief fibrinolytic enzyme is serrapeptase. Serrapeptase has the ability to reduce chronic pain, systemic inflammation and systemic fibrosis.

Is VitalzymSEB stronger than Vitalzym?
According to the formulator, it is impossible to compare the two blends in terms of strength as they were formulated for different results. Vitalzym is better for pain, inflammation and systemic fibrosis. It will also help with cleansing the blood and reducing vascular inflammation. VitalzymSEB is better for cleansing excess fibrin in the blood and possibly arterial plaque.

Should I reduce my Vitalzym dosage while taking VitalzymSEB?
There may be a small amount of crossover between Vitalzym and VitalzymSEB. It is recommended to continue with your current Vitalzym dosage if taking for pain and inflammation, however one may be able to slightly reduce their Vitalzym dosage if taking for wellbeing.

The statements made herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.


According to the formulator, it is impossible to compare the two blends in terms of strength as they were formulated for different results. Vitalzym is better for pain, inflammation and systemic fibrosis. It will also help with cleansing the blood and reducing vascular inflammation. VitalzymSEB is better for cleansing excess fibrin in the blood and possibly arterial plaque.

Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

The Real Causes of Heart Attacks
By: Dr. William Wong, ND, PhD

 

For the last 30 years people have thought the cause of heart disease was, cholesterol. That was the boggy man orthodox medicine waved in front of Americans noses as the do all end all of heart disease. Control your cholesterol and you'll avoid heart disease. So for the last 30 years Americans have dramatically lowering their fat intake: who eats steady diets of deep fried foods anymore, who still cooks with lard, even Kentucky Fried Chicken changed their cooking technique and name to reflect the nations wanting to reduce their fat intake. And, by and large the targets that were set by medicine were met. In 1966 after Harvard's famous Framingham cholesterol study, the public was told that a cholesterol count of 300 was good. That was easily accomplished mostly via diet alone, but the rate of heart disease and heart attack did not go down!

Then in the 80's the number was dropped to 244, that was the gold standard for a while. That figure was harder to get to, both diet and exercise were needed by most to accomplish the task but again by and large the target was met. Again there was no drop in heart disease or in the death from heart attack figures. Instead of wondering whether they were chasing the wrong boggy man, as physicians the world over were telling US doctors, American heart health authorities stuck to their guns about cholesterol being the near do all end all of heart disease. There was even a Niteline show with Ted Koppel in the early 90's where cardiologists from around the world were gathered and asked why American's had so much heart disease! The foreign docs pounded the American experts for their dependence on cholesterol as their most important marker of heart health.

Around this same time drug companies had developed a slew of cholesterol lowering drugs called Statins. This gave even more incentive to stick to their guns about cholesterol, and the authorities lowered the target figure once again to under 200. Now most people needed drugs to get close to that figure. (Could there have been any relation between the invention of the drugs and the lowering of the cholesterol target to one that most folks couldn't meet with out the drugs? No, couldn't be that would be a conspiracy theory)! By the way these cholesterol drugs have been found to cause lower extremity nerve damage, decrease memory, increase chances of breast cancer, cause liver damage and death. (1,2). A press release about one of these drugs in December of 2003 stated that the drugs was in itself causing heart attacks!

All this silliness about cholesterol continued until the late 90's when a good number of very young, extremely fit 30 to 40 somethings dropped dead of heart attacks. Autopsy's found they had not a whit of athero sclerotic (cholesterol) plaque anywhere in their arteries! So what killed them!

Well, what these victims did have were very, very high levels of inflammation in their blood vessels. It was then that the work of a researcher who had been fired from Harvard for saying cholesterol was not the primary cause of heart attacks, was rediscovered and realized by medical world to be true. This researcher had said that vascular inflammation could close the blood vessels as tightly as athero sclerotic plaque could and bring on a heart attack. He asserted that measuring a marker for inflammation called C Reactive Protein was a better indicator of heart health then measuring cholesterol! (Later in the decade he sued Harvard for wrongfully firing him and won).

So, first and foremost we have the primary cause of heart attack, vascular inflammation. What is this and how does it set in? Vascular inflammation is a result of stress, some thing we have in abundance and something those high intensity 30 and 40 somethings who keeled over had multiplied in their lives. Those heart attack victims had been under stress since school making good grades, jumping into careers, starting and managing families, exercising or over exercising regularly (many were marathoners and tri athletes); in other words most of every second of every day was filled with activity and the rush of getting from one task to another.

In causing vascular inflammation another effect kicks in. Inflammation is a form of trauma that creates fibrosis. Yes, our old nemesis returns! When the intima, (inside wall of a blood vessel), swells they are irritated and stretched. The body reacts to this insult by weaving fibrin into the walls to strengthen what it sees as a weak point. This fibrin causes the blood vessels to lose their expandability and elasticity. This is the primary stage of hardening of the arteries. It's only in the later stages of hardening that spider webs of fibrin grow on weak points inside the lumin (hole) in the artery and on that matrix cholesterol plaque accrues and plugs up the works making matters worse. During this entire process if the stress remains the inflammation remains and the cycle continues.

So it's the inflammation that kicks off the process of hardening of the arteries and athero sclerotic plaque. The combination of the swelling and plaque closing the lumin of an artery can cause trouble. But remember it has been found that the inflammation alone may be severe enough to close off the blood vessel creating a heart attack!

Mineral deficiencies can make matters worse still by creating irregularities in the heart beat. Calcium is the electrolyte responsible for muscular contraction, magnesium is the mineral electrolyte responsible for muscular relaxation. Muscles in magnesium deficit spasm. Remember calcium = contract magnesium = relax. When the body lacks magnesium then calcium gets into the magnesium channels producing a contract signal instead of the contract - relax signal and there you have arrhythmias.

So what's a true all encompassing plan to increase heart health? Any scheme to better the health of the heart and blood vessels needs to start at the source, stress and it's resultant inflammation. I'm supposing that most folks out there have their lives so regimented that lowering the stress levels likely is not possible so we'll work from the next stage.

It goes with out saying that if you can lower your stress levels by doing less, compressing less into your day and worrying less, that should be done. But for most folks these crazy days that's much easier said than done. So, it behooves us to do the things that can be done so as not to become a statistic.


References:
1) www.mercola.com
2) Mortimer, J.E., Axelrod, R., Zimbru, K. Sentara Norfork General Hospital, Norfolk VA.: Effect of Statins on breast cancer incidence. Proc An Soc Clin Oncol, 22, page 93, 2003.

 

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Vitalzym SEB-World Nutrition FREE SHIPPING

Vitalzym SEB-World Nutrition FREE SHIPPINGCleanse the blood of excess fibrin, reduce vascular inflammation. Available in 300 capsules
Sale Price $129.99

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Vitalzym - World Nutrition Systemic Enzymes Free Shipping Volume Discount available on 3+ bottles of 450 Caps please call for details

Vitalzym - World Nutrition Systemic Enzymes Free Shipping Volume Discount available on 3+ bottles of 450 Caps please call for detailsAvailable in 90, 270, 450 Caps Without enzymes life could not exist. Anti Inflammatory/ Pain Relief
Sale Price $114.00

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Ingredients for Vitalzym SEB: Proprietary Blend contains SEBkinase (blend of Nattokinase and Serratiopeptidase), Bromelain, Papain, Lipase, Protease, Rutin, Amla, CoQ10, and Magnesium